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Latest Arthritis And Other General News Headlines

Protecting Teens From Dating Violence
Obsessive phone calls and text messages can snowball into teen dating abuse.

E-Mails Make Teens Behave on MySpace
When teens were warned about risky online behavior, some cleaned up their act.

Preventing weight gain associated with lithium
Goodwin and Goldstein (2003) advocate the following measures to prevent weight gain in patients on lithium carbonate: Dietary/lifestyle measures Encourage daily physical exercise Restrict fluid intake to non-sugary liquids (e.g., water, diet soft drinks) Avoid intake of simple carbohydrates, particularly early in the day (lithium may induce mild hypoglycemia, causing patients to increase caloric intake as they ?chase? their blood sugar through the day) Medical/pharmacological measures Measure free T4 and supplement thyroid hormone if necessary (T4 at or below the lower quartile of normal may indicate hypothyroidism, another cause of weight gain If possible, avoid concurrent medications with additive weight gain effect Consult with primary care physician about other options if weight gain exceeds 5 lbs despite preventive measures Ref: - Goodwin, F.K. & Goldstein, M.A. (2003) Optimizing lithium treatment in bipolar disorder: a review of the literature and clinical recommendations. Journal of Psychiatric Practice, 9, 5, 333-343.

Diet
Coffee May Also Reduce Risk Of Diabetes

The Dangers of 'Third-Hand' Smoke
Cigarette chemicals that linger on clothes could cause harm, a new study finds.

Heart-Wrenching Return Home for Travoltas
A friend told "GMA" of the moment where Travolta identified his son's body.

Letter Of The Week
— from Karen Lynne Lambert
“Regardless of how politics may try to dissuade or delude you, all you need to know is that my [chronic fatigue immune dysfunction syndrome] is infectious. It is contagious. And it is spreading, unleashed, in the world's population. I am not afraid to say that I have AIDS without HIV — my second official clinical diagnosis. I am equally as unafraid of saying the most obvious thing about chronic fatigue syndrome: It sure does look like AIDS to me. We talk openly about preparing for an impending avian flu pandemic. Why not talk about the HIV-negative AIDS epidemic that already exists (and is spreading) amongst us?”

Pharmacotherapy for body dysmorphic disorder
After a detailed review of the literature, Allen and Hollander (2000) concludes that SSRIs are the first-line therapy for body dysmorphic disorder, with the dosage and length of trial similar to those used for OCD. In refractory cases, especially if delusional conviction is present, augmentation with low doses of atypical antipsychotics might be effective. Other augmentation strategies that are clinically used include adding bupropion, gabapentin, or stimulants such as dexamphetamine to the SSRI therapy. Ref: - Allen, A. & Hollander, E. (2000) Body dysmorphic disorder. The Psychiatric Clinics of North America, 23 (3), 617 ? 628.

Use of atypical antipsychotics in children and adolescents
Evidence on the efficacy and safety of with schizophrenia is limited. Toren et al. (2004) reviewed the literature on use of atypical antipsychotics in children and adolescents with schizophrenia. The major findings were: Risperidone, and possibly also olanzapine, may be the drugs of choice in children with comorbid tic disorders. Ziprasidone may be administered as an augmenting agent in children and adolescents with schizophrenia and comorbid anxiety and mood disorders. Risperidone, olanzapine and clozapine are effective in the treatment of aggression and mania. In children and adolescents receiving clozapine, olanzapine and quetiapine, particularly those with obesity or a family history of diabetes mellitus, fasting blood glucose and lipid levels must be monitored frequently. Weight gain might be better controlled when the children and their parents are properly informed about this adverse effect and diet is regulated. Hyperprolactinaemia is another major disadvantage of the atypical antipsychotics, especially risperidone. Hyperprolactinaemia can lead to hypogonadism-induced osteoporosis, galactorrhoea, gynaecomastia, irregular menstruation and sexual dysfunction. Other atypical antipsychotics, namely olanzapine and ziprasidone, have been reported to be prolactin sparing in adults, but may not be completely devoid of hyperprolactinaemic effects in children and adolescents. Thus, prolactin levels should be assessed routinely in young patients treated with atypical antipsychotics. Further, children and adolescents with hyperprolactinaemia-related effects should be switched to a prolactin-sparing agent, such as quetiapine. The use of typical antipsychotics has been limited to patients who are resistant to atypical antipsychotics, intolerant to their adverse effects, or require injections or depot preparations. Ref: - Toren, P., Ratner, S., Laor, N. & Weizman, A. (2004) Benefit-risk assessment of atypical antipsychotics in the treatment of schizophrenia and comorbid disorders in children and adolescents. Drug Safety, 27, 14, 1135-1156.

Rise in Healthcare Spending Slows
Increased use of generic drugs could be behind the slowdown, researchers say.

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